Subclonal composition of CNS and splenic compartments. (A) Schematic of experimental design. (B) Clonal composition of CNS (leptomeninges) and splenic compartments of mice transplanted with primograft samples #WB51 and #L707. Pie charts show frequencies of most prevalent integrations in paired CNS and spleen samples from 2 mice per sample. Pie chart colors are unique to each mouse spleen-meninges pair and do not represent the same clones between different mice. Corresponding tables of integration site frequencies for each mouse are given in supplemental Figure 5.