Genomic location of the 51 genes underlying IPDs. Circos diagram¹²⁰  illustrating the location of known IPD genes across human chromosomes. Track 1: Cytoband with chromosome name with centromeres in blue. Track 2: Genomic location of 51 established IPD genes and the year in which variants in the gene were first identified as a cause of IPD in humans in brackets. Gene names in red represent genes identified by HTS. Track 3: Log₁₀ of the number of amino acids encoded by the reference CCDS transcript. Log₁₀ scale is indicated at 12 o’clock. Track 4: Log₁₀ of the number of rare variants predicted to affect amino acid sequence observed in 6390 individuals enrolled to the NIHR BioResource–Rare Diseases. Log₁₀ scale is indicated at 12 o’clock.