FXI binding peptides with the DFP motif. (A) Alignment of peptide sequences from the random screen, with 37 peptides shown containing the DFP tripeptide. (B) Peptide motif overview calculated using MEME software for the 37 FXI-binding DFP peptide sequences. (C) Location of DFP pentapeptide sequences in the proteins HK (KNG1_HUMAN), laminin (LAMA1_HUMAN), and collagen V (CO5A1_HUMAN) identified using PROSITE software.