Best model fits to neutrophil DNA enrichment data in subjects labeled with deuterium-labeled glucose. Subjects were labeled with deuterium-labeled glucose (6,6-2H2-glucose) for 10 hours (C36R and C41), 4 hours (C42), 3 hours (C46, C48, C49, and C50), or as a single oral dose (C59 and C60). Circles represent measured fractional enrichment of deoxyadenosine in blood neutrophil DNA; lines represent best fits of the model (Equations 5 and 6) to the data.