In vivo single-agent venetoclax responses in 2 additional MLLr-ALL xenografts. (A-B) Xenografts were treated with venetoclax (100 mg/kg for 21 days, dotted line) or vehicle control (solid lines). Gray lines represent results from individual mice, whereas the black lines represent the median outcome for each cohort. Left panels represent the %huCD45⁺ of individual mice over time, whereas the right panels show the proportion of mice remaining event free. (C) Summary of xenograft responses to venetoclax.