iPEPs after 9 cycles of induction vs maintenance therapy. iPEPs of CD4 and CD8 T lymphocytes and of CD56^dim and CD56^bright NK cells in PB samples from high-risk patients with SMM (n = 13) studied after 9 cycles of induction therapy with LenDex vs during maintenance with lenalidomide (Len) at least 3 months after dexamethasone discontinuation. In the PCA graphical view, every patient is represented by a unique color, with squares representing iPEPs from PB samples studied after induction therapy and circles representing iPEPs during maintenance.