Restaging FDG-PET/CT and contrast-enhanced CT at 19 weeks demonstrates interval resolution of FDG uptake in a liver lesion. Restaging contrast-enhanced CT shows interval decrease in size of the hepatic lesion (arrow). Because the lesion did not disappear, this patient achieved a PR by immune-related response criteria, whereas the absence of FDG uptake on FDG-PET/CT is a CR by the Lugano Classification. There was also a complete metabolic response in the mediastinum and right upper abdomen (asterisks).