Figure 4.
Figure 4. The T-cell transcriptome of breakthrough acute GVHD. (A) Heatmap of the top 25 gene sets enriched in the breakthrough acute cohort using ssGSEA and (B) constellation map visualization. (C) Box plots of expression data (Log2 normalized fluorescent intensity signal) for MKI67 and granzyme B (GZMB). Horizontal significance bars denote comparisons with a moderated t statistic < 0.05 corrected for multiple hypothesis testing.

The T-cell transcriptome of breakthrough acute GVHD. (A) Heatmap of the top 25 gene sets enriched in the breakthrough acute cohort using ssGSEA and (B) constellation map visualization. (C) Box plots of expression data (Log2 normalized fluorescent intensity signal) for MKI67 and granzyme B (GZMB). Horizontal significance bars denote comparisons with a moderated t statistic < 0.05 corrected for multiple hypothesis testing.

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