Constitutive and induced VWF expression from BOECs. BOECs constitutive VWF expression from unstimulated cells as well as PMA (160 nM, 1 hour) stimulated release of BOEC WPBs (N = 3; *P < .05; **P < .01; ***P < .001). Underlined significance stars indicate significant increase in VWF release with PMA stimulation. Significance stars without underlining indicate a significant difference in expression compared with unstimulated BOECs from 3 normal controls. The average expression from the normal BOECs was set to 1 and the patient BOECs were presented relative to the normals.