Decreased FL size after global deletion of Vegfc at E7.5. (A-D) Representative images of VciΔR26 embryos at E13.5 and E15.5. Note the smaller liver size in VciΔR26 embryos. Bar represents 2 mm. (E) Liver weight in E13.5 to E15.5 embryos (n = 3-8 per group; mean ± standard error of the mean [SEM]; *P < .05). (F) Representative hematoxylin and eosin FL sections. Bar represents 50 μm. (G) Activated caspase-3 and 4′,6-diamidino-2-phenylindole (DAPI) staining. High magnification images are shown on the right. Bar represents 200 μm.