Transcriptional signatures of PBMCs in patients with AML exhibiting robust vs weak CRT exposure on blasts. (A-B) Expression levels of genes from the Human Immune Panel TaqMan low-density array in PBMCs from 13 CRT^Hi vs 13 CRT^Lo patients with AML prior to the initiation of induction chemotherapy (A), or at recovery of normal hematopoiesis (B). The Mann-Whitney test was employed to assess intergroup variations. (C) qRT-PCR–assisted quantification of CD8A, CD28, CXCR3, IFNG, IL2, IL2RA, TBX21, FASLG, GNLY, GZMB, PRF1, CCL5, CCR4, CCR4, CCR5, CD40LG expression levels in PBMCs from 13 CRT^Hi vs 13 CRT^Lo patients with AML prior to the initiation of induction chemotherapy, or at recovery of normal hematopoiesis. Box plots: lower quartile, median, upper quartile; whiskers, minimum value, maximum value.