Figure 1
Figure 1. Analysis of Gata2 expression in hematopoietic progenitors and DCs. (A) DC differentiation pathway in mice. (B) Relative levels of Gata2 mRNA in Lin−Sca-1+Kit+ cells (lin−IL-7Rα−c-kithiSca-1hi), CMPs (lin−IL-7Rα−c-kithiSca-1−FcγRII/IIIintCD34+), GMPs (lin−IL-7Rα−c-kithiSca-1−FcγRII/IIIhiCD34+), CLPs (lin−IL-7Rα+c-kitintSca-1int), CDPs (lin−IL-7Rα−c-kitint∼loFLT3+M-CSFR+CD11c−), cDCs (B220−CD11chi), pDCs (B220+CD11clo), and BM-DCs (FLT3-l–induced DCs and GM-CSF–induced DCs) generated in vitro in the presence of FLT3-L or GM-CSF, respectively. Values are presented relative to those of Gapdh mRNA. Data represent the averages of 3 independent experiments and are expressed as means ± SDs. ND, not detectable.

Analysis of Gata2 expression in hematopoietic progenitors and DCs. (A) DC differentiation pathway in mice. (B) Relative levels of Gata2 mRNA in LinSca-1+Kit+ cells (linIL-7Rαc-kithiSca-1hi), CMPs (linIL-7Rαc-kithiSca-1FcγRII/IIIintCD34+), GMPs (linIL-7Rαc-kithiSca-1FcγRII/IIIhiCD34+), CLPs (linIL-7Rα+c-kitintSca-1int), CDPs (linIL-7Rαc-kitint∼loFLT3+M-CSFR+CD11c), cDCs (B220CD11chi), pDCs (B220+CD11clo), and BM-DCs (FLT3-l–induced DCs and GM-CSF–induced DCs) generated in vitro in the presence of FLT3-L or GM-CSF, respectively. Values are presented relative to those of Gapdh mRNA. Data represent the averages of 3 independent experiments and are expressed as means ± SDs. ND, not detectable.

Close Modal

or Create an Account

Close Modal
Close Modal