Figure 5. Many endogenous myeloid progenitors are replaced by donor myeloid progenitors upon the transplantation of HSCs into unconditioned mice. Unconditioned CD45.1 × CD45.2 recipients were transplanted with 2.5 × 105 purified CD45.2 HSCs. Bone marrow was analyzed for the numbers of total nucleated cells (A) and donor (CD45.2+), endogenous (CD45.1+CD45.2+), and total GMPs (B) 13 weeks after transplantation (n = 3). All error bars represent standard deviations of the means.
Figure 5.

Many endogenous myeloid progenitors are replaced by donor myeloid progenitors upon the transplantation of HSCs into unconditioned mice. Unconditioned CD45.1 × CD45.2 recipients were transplanted with 2.5 × 105 purified CD45.2 HSCs. Bone marrow was analyzed for the numbers of total nucleated cells (A) and donor (CD45.2+), endogenous (CD45.1+CD45.2+), and total GMPs (B) 13 weeks after transplantation (n = 3). All error bars represent standard deviations of the means.

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