Figure 5.
Fibrin formation is dependent on TF expression by myeloid cells. Transient platelets (A) and fibrin formation (B) were compared between myeloid cell-specific TF-deficient mice (TFf/f LysM-Cre+/−) with controls (TFf/f LysM-Cre−/−) following IVC stenosis over 6 hours (C) (n = 3; 3-4 visual fields per mouse; mean ± SD). Scale bar: 100 μm. Consecutive measurements were evaluated by 2-way ANOVA followed by Bonferroni posttest. **P < .01; ***P < .001. h, hour; n.s., not significant.