TET3 knockdown led to reduced cell growth accompanied by increased apoptosis of late-stage erythroblasts. (A) Growth curves of luciferase-shRNA and TET3-shRNA–transduced cells. (B) Representative plots of 7-AAD and Annexin V staining. (C) Quantification of Annexin V-positive cells at indicated days. The results are from 3 independent experiments. *P < .05; **P < .01. 7-AAD, 7-aminoactinomycin D.