Feature of MYC and BCL2 mutations and CN alterations. (A) Lollipop plots showing the type and location of MYC and BCL2 mutations. Top plot represents mutations observed in ABC-DLBCL cases, and bottom plot represents those observed in GCB-DLBCL cases. (B) GISTIC gain score plot (left). Copy number heat map visualized by Integrative Genomics Viewer (IGV), illustrating gain affecting the MYC locus (dashed line; top right) on chromosome 8 and BCL2 locus (dashed line; bottom right) on chromosome 18 in representative DLBCL samples.