Inhibition of PI3Kδ synergizes with dex in regulating cell-death effector genes. (A) Change in gene expression measured by quantitative polymerase chain reaction (qPCR) in response to 2 concentrations of dex at 24 hours in 3 cell lines. (B) Change in gene expression measured by qPCR in response to 2 concentrations of CAL-101 alone and in combination with 2 concentrations of dex (C) at 24 hours in the same cell lines. Experiments represent at least 3 biological repeats. *P ≤ .05 (see “Methods” for details). Dashed boxes highlight genes whose regulation is restored by CAL-101 (idela).