Figure 4.
Three distinct clusters of intracellular marker activation seen in the CD33+ subset of CD49f+ cells. Spearman correlations were calculated between each intracellular marker pair for all cells in the CD33+ subset of the CD49f+ cells following their stimulation with or without 5 GFs. (A) Pairwise correlations are shown between each marker with the color intensity indicating degree of correlation. Markers are ordered based on hierarchical clustering. (B) A network model with edges based on the correlation. Edges were included only when Holm-corrected P values were ≤.01 and the absolute value of Spearman ρ was ≥0.2. Node layout was calculated using the Fruchterman-Reingold algorithm with edge weights of 102abs(ρ).