Figure 1.
Representative flow volume. (A) Representative flow volume loop of a patient with BOS (red) compared with a patient with normal exhalation (gray) (left). Spirogram representation of BOS (red) as compared with normal lung volumes (gray) and those of a patient with sclerotic GVHD (blue) or extrapulmonary restriction (right). Within the spirogram, the FEV1 is shown first, then the FVC and RV, and then the TLC (TLC = RV + VC). Below the spirogram are representative PFT parameters for each of the 3 groups of patients: normal in gray, BOS in red, and sclerotic GVHD in blue. (B) Representative flow volume showing the notch characteristic of tracheomegaly or tracheobronchomalacia. Panel A reprinted from Williams et al10 with permission.
