Figure 3.
TK fusion genes in myeloid/lymphoid neoplasms with eosinophilia. As of October 2016, 72 tyrosine kinase fusion genes have been described. In conjunction with cytogenetic/fluorescence in situ hybridization and genetic testing, morphologic evaluation and flow cytometric immunophenotyping is required to identify whether such molecular abnormalities are associated with an acute or chronic myeloid neoplasm and/or a B- or T-cell lymphoblastic leukemia/lymphoma. Figure courtesy of Professor Nicholas C. P. Cross.