Figure 3.
Improvement of T-cell repertoire and thymic output post-GT. (A) T-cell repertoire analysis by TCR spectratyping pre- and post-GT in CD4+ and CD8+ T cells. (B) sjTREC content in CD4+ (red line) and CD8+ (blue line) T cells (dotted line corresponds to the tenth centile for the patient’s age group). TRECs, T cell receptor excision circles.