Figure 5.
Upregulation of Csf1r in monocyte subsets is impaired in Cebpb−/− mice. (A) Csf1r mRNA expression in purified hematopoietic populations (n = 3). (B) Csf1r mRNA expression in purified hematopoietic populations obtained from BM of WT or Cebpb−/− mice (n = 3). (C) Csf1r mRNA expression in purified monocyte subsets obtained from the PB of WT or Cebpb−/− mice (n = 3). (D) Flow cytometric analysis of CD115 (Csf1r) expression on Ly6C+ (left) and Ly6C− (right) monocytes in the PB of WT (filled lines, n = 3) and Cebpb−/− (unfilled lines, n = 3) mice. Data are presented as mean ± SD. **P < .01, ***P < .001. Numbers indicate the percentage of cells in the adjacent boxed area. MFI, mean fluorescence intensity.