QOL assessment. (A) Mean functional status scale score according to the EORTC QLC-C30 (physical, role, emotional, and social functioning); higher scores on the combined global health status/QOL and functional scale represent a better level of functioning. (B-C) Mean symptom scale scores according to the EORTC QLC-C30 (fatigue, nausea/vomiting, pain, dyspnea, insomnia, appetite loss, diarrhea, constipation, and financial impact); higher scores on symptom scale correspond to a higher level of symptoms. (D) Mean Lee Chronic GVHD Symptom Scale scores.