Inhibition of BCR-dependent Akt activation by ILT3 requires SHIP-1. (A) Representative immunoblot of CLL cells, treated with the SHIP-1 inhibitor 3AC or mock treated, and stimulated as indicated for 3, 7, and 15 minutes. (B) Quantitative immunoblot analysis (n = 4 patients). Shown are mean values ± SD. *P < .05.