Antibody reactivities against skin cell membrane antigens. Healthy donor (n = 90). No cGVHD indicates patients with no cGVHD (n = 85). cGVHD indicates patients with active cGVHD (n = 106) as described in “Materials and methods” cGVHD-T indicates patients with active cGVHD and receiving intensive treatments as described in “Materials and methods” (n = 93). *P < .0001. (A) Antibody reactivity was tested with FLISA using membrane proteins from the skin keratinocyte cell line (CCD1106) as antigens. (B) Antibody reactivity was tested with FLISA using membrane proteins from the skin fibroblast cell line (Detroit 551) as antigens. HD, healthy donor.