Myc and DLBCL. Approximately one-third of DLBCLs are positive for myc and bcl-2 by immunohistochemistry (double expressor); most of these occur in ABC DLBCL. The new WHO category of high-grade B-cell lymphoma with myc and bcl-2 and/or bcl-6 rearrangements (double hit) usually, but not always, falls in the double-expressor group, but in the GCB subtype. Additionally, morphology of this group may include Burkitt-like lymphoma.