Associations among ECV, diastolic dysfunction, and markers of restrictive physiology. Box-and-whisker plots showing differences in (A) ECV, (B) hemoglobin, (C) LAVi, (D) LVEF, and (E) NT-proBNP between participants with diastolic dysfunction and normal diastolic function (normal). (F) Difference in TRV between participants with diastolic dysfunction and normal diastolic function. Participants >21 years are shown in green. P value for the difference in the overall group is shown in black, and P value for the difference among participants >21 years is shown in green. Each box in panels A-F extends from the 25th to 75th percentile, and the line in the box is plotted at the median while the whiskers extend from the smallest to the largest value. (G-I) Linear regression of ECV and (G) lateral E/e′ ratio, (H) tricuspid E/A ratio, and (I) log-NT-proBNP.