Effect of HSCT in clinical features resolution. Dark gray squares represent the presence of a clinical feature/phenotype. Light gray squares represent major improvement in clinical features. White squares represent complete resolution of clinical feature. Each patient is presented by 2 attached columns (before and after transplant) for comparison. Follow-up time post-HSCT for each patient is shown in months (first row). Severe infections represent any viral, bacterial, or fungal infection that required antiviral or antifungal treatment or led to sepsis. FTT, failure to thrive.