Cks1 deficiency inhibits pretumor B-cell proliferation in LMP2A/λ-MYC mice. The effects of Cks1 status on the cell cycle phases of purified splenic pretumor B cells from 4-week-old mice are indicated in (A) pie charts and (B) column graphs. (C) The percentages of Ki-67–positive cells in purified splenic pretumor B cells. Data were calculated by 1-way ANOVA with post hoc multiple comparison tests. The statistical differences of Cks1 knockouts against their controls are indicated with thick lines. Data represent the mean ± standard deviation. *P < .05, **P < .01, ***P < .001, and ****P < .0001.