Flow of outcomes among patients enrolled in the study within 3 months after beginning systemic treatment of chronic GVHD. Patients who received second-line systemic treatment before enrollment in the study were excluded from this analysis. Fifteen of the 32 patients with relapse died within the first year after enrollment. CR/PR indicates complete or partial response at the time of assessment; SD/PD indicates stable or progressive disease at the time of assessment. *This category includes patients who were alive without recurrent or progressive malignancy at 1 year but did not have the intended assessment.