Functional taxonomy of AML patient samples based on differential drug response profiles between stroma-derived CM and standard culture conditions. Unsupervised clustering of the patient samples based on drug sensitivity differences between CM and MCM (deltaDSS) separates the samples into 5 subgroups (A-E). AML samples with a FLT3-ITD (groups A-C) are distinguished from samples without the alteration (groups D-E).