Merozoites invasion with or without HP6H8 treatment. (A) Timeline of the merozoite invasion process in this study. (B) The development of merozoites during invasion in normal conditions observed with a TEM. Scale bar, 500 nm. (C) Merozoite invasion after HP6H8 treatment observed with a TEM. Scale bar, 500 nm. (D) Model of key receptors and ligands participating in the invasion process. (Black arrow) HP6H8 stopped PV formation by blocking the interaction between CD147 and RAP2.