Survival analysis according to the BCL2 IHC scores. (A-B) PFS and OS of patients with DLBCL in the training set stratified by 4-grade BCL2 IHC scores, from 0 to 3+. Between score 3+ and 2+: HR for PFS = 2.41; 95% CI, 1.49-3.90; P* = .001; HR for OS = 1.98; 95% CI, 1.12-3.49; P* = .030. (C-D) PFS and OS of patients with DLBCL in validation set. Between score 3+ and 2+: HR for PFS = 1.86; 95% CI, 1.09–3.17; P* = .03. HR for OS = 2.44; 95% CI, 1.31–4.54; P* = .007. (E-F) PFS and OS of patients with DLBCL in the entire cohort stratified by 3-grade BCL2 scores; 0 to 1+, 2+, and 3+. (G-H) PFS and OS of patients with GC-type and (I-J) with non-GC–type DLBCL based on BCL2 scores, 3+ or 0 to 2+. P**, BCL2 score 2+ vs score 0 to 1+; P**, BCL2 score 3+ vs score 2+.