Depiction of the effect of inhibiting NOTCH signaling at day 2 of iPS cell differentiation. In comparison to the control condition (A), addition of the gamma secretase inhibitor RO4929097 (B) or DAPT (C) increased the presence of cells with blood-like appearance (arrow) surrounding treated embryoid bodies after 14 days of culture. DAPT, 7{N-[N-(3,5-difluorophenyl)-l-alanyl]-S-phenyl-glycine t-butyl ester}; DMSO, dimethyl sulfoxide. See supplemental Figure 5B in the article by Li et al that begins on page 191.