Levels of chemerin isoforms before and after contact phase activation in controls and FXI-deficient (FXID) patients. (A) Total chemerin (PAN), chem163S, chem158K, chem157S, and chem155A levels in PPP from patients (n = 8) and matching controls (n = 8) were determined using specific ELISAs as described under “Experimental procedures.” Horizontal lines show the mean. *P < .05; **P < .01. (B) The correlation between % FXI levels in plasma and the level of chem163S in plasma was compared (n = 18). Pearson’s correlation coefficient R² and the P value are shown.