Rescue of hemoglobinization in AOA treated differentiating MEL cells. ALA and DMK but not DES rescue hemoglobinization of AOA treated MEL cells at 72 hours. MEL cells were treated with AOA and/or metabolites at erythroid differentiation induction (A) and at 48 hours postinduction (B). Data shown are averages of 3 determinations. Error bars represent mean ± standard deviation. **P < .01. SA, succinylacetone.