Phylogenetic analysis for HLA-DPB1 alleles. Phylogenetic trees were constructed using the Neighbor-Joining method. Numbers on the branches are bootstrap support values. Blue and red letters indicate DP2 group (rs9277534: A) and DP5 group (rs9277534: G) alleles, respectively. (A) The 12 149-bp nucleotide alignment for HLA-DPB1 whole gene was used. (B) The 2668-bp nucleotide alignment for the region from exon 3 to 3′UTR was used. (C) The 264-bp nucleotide alignment for exon 2 was used.