The top panel shows the germline configuration of the 14q32 plasmid and cosmid probes. The second panel shows how 14q32 would look after VDJ recombination and class switching. The third and fourth panels show the reciprocal translocation products observed in KMS12 cells, while the bottom panel represents the germline configuration of the 11q13 cosmid and P1 probes. All probes are described in Vaandrager et al,2 except cosIg6,4 cCL11-505 (JCRF, Tokyo, Japan), the γ plasmid,5 and the α plasmid.⁶