Fig. 3.
Effect of PTX on the recruitment of 111In-eosinophils in response to intradermal injection of C5a, LTB4 , or PAF. Eosinophils were pretreated for 2.5 hours with PTX (1 μg/mL, see the Materials and Methods) or vehicle. The cells were then labeled with 111In and injected intravenously (2.5 × 106 cells/animal) into recipient guinea pigs. 111In-eosinophil recruitment was measured 1 hour after the intrademal injection of PAF (10−12 to 10−10 mol/site), C5a (10−12 and 10−11 mol/site), and LTB4 (10−12 to 10−10 mol/site). The dashed line across the graph represents background values in response to injection of saline. Results are the mean ± SEM of five pairs of animals.
