Morphological characteristics of FDC-P1/MAC-11 cells treated with c-fes ODN before and after induction to macrophage differentiation by 48 hours of PMA treatment. (A) ODN untreated FDC-P1/MAC-11 cells; (B) ODN untreated FDC-P1/MAC-11 cells induced to macrophage differentiation with PMA; (C) macrophage morphology observed when FDC-P1/MAC-11 cells, pretreated for 5 days with the mFES-IP1, 2, and 3 ODN, are induced to differentiate with PMA; (D) morphology of FDC-P1/MAC-11 cells pretreated with mFES-AS1, 2, and 3 ODN and PMA induced. This panel is representative of the results obtained by several different experiments. Original magnification ×1,000.