Fig. 5.
Northern blot analysis of p21Waf1 in typical and aggressive mantle cell lymphomas. The aggressive MCL 441 shows a loss of p21Waf1 mRNA expression. This finding is concordant with the lack of protein expression in this case (shown in Fig 3). The blots were stripped of the p16INK4a probe and rehybridized with the 28S probe as a loading control.