Schematic diagram of the wild-type proteins and deduced chimeric proteins. Vertical arrowheads indicate breakpoints of both DDX10 and NUP98. Regions that correspond to the structural or functional domains of the proteins are also shown: DEAD, DEAD motif; Heli, putative RNA helicase domain; charged, charged amino acids motif; FG, FG peptide repeat motif; RNA bind, putative RNA binding domain.