Mean (± SE) plasma concentrations of prothrombin fragment F1 + 2 and TAT complexes after intravenous injection of LPS (lot EC-5; 2 ng/kg) at t = 0 hours in subjects receiving either (○) TNFR:Fc (6 mg/m²; n = 6) starting at t = −0.5 hours or (•) vehicle (n = 6). NS, nonsignificant for the difference between treatment groups.