Mean (± SE) plasma concentrations of IL-6, IL-8, and IL-10 after intravenous injection of LPS (lot EC-5; 2 ng/kg) at t = 0 hours in subjects receiving either (○) TNFR:Fc (6 mg/m²; n = 6) starting at t = −0.5 hours or (•) vehicle (n = 6). P value indicates the difference between treatment groups. NS, nonsignificant.