Fig. 1.
Diminished (A) DNA synthesis and (B) cell cycle progression induced by IL-2 in NK3.3 cells cultured in CYS(+) (closed symbols) or CYS(-) medium (open symbols). (A) [3H]-TdR incorporation. (B) Percentage of NK3.3 cells in G1 (squares) or S (circles) phase. NK3.3 cells were depleted of intracellular thiols before initiation of experiment as described in Materials and Methods. Data are from one experiment, representative of two to three independent experiments.