Changes in plasma markers of DIC over time after the administration of varying doses of AT concentrate 30 minutes postinfusion of DIC-SA. *DIC-SA alone group different from all other groups (P ≤ .05). ρDIC-SA alone group different from 1,000 IU/kg, 500 IU/kg, and 250 IU/kg groups (P ≤ .05). †DIC-SA alone group different from 1,000 IU/kg and 500 IU/kg groups (P ≤ .05). ¶1,000 IU/kg and 500 IU/kg groups different from 125 IU/kg and 250 IU/kg groups (P ≤ .05).