Partial approximate map of the human MHC region with the consensus haplotypes in Jewish and non-Jewish CA patients. TNF alleles with statistically significant differences in frequencies in patients compared with controls are written in bold. The borders for the class-III region are defined by the HLA class II (DRB1 locus) and HLA class I (B locus). The allele assignment for the HSP70-1, -2, and the HLA-DR and HLA-B loci was summarized from our previous publications4 21 (see text for details).