Prognostic significance of the combination of CD45 and CD20 intensity. Kaplan-Meier survival plots of all patients classified by risk group based on intensity of CD45 and CD20 expression. CD45 poor risk implies < 75th percentile of intensity; CD20 poor risk implies < 50th percentile of intensity. ——, CD45 and CD20 good risk (57% of patients); –––, CD45 good risk, CD20 poor risk (24% of patients); ---, CD45 poor risk, CD20 good risk (11% of patients); ⋅⋅⋅, CD45 and CD20 poor risk (8% of patients). The curves are significantly different (P < .001).