Fig. 4.
Effect of diarrhea-associated HUS plasma on EC of different tissue origin. DNA histograms were obtained with microvascular EC of dermal, cerebral, and pulmonary origin, as well as large vessel EC derived from coronary artery, after 16 hours of exposure to 1% plasma from a 2-year-old infant with acute, diarrhea-associated HUS. A0 values greater than background were not obtained from any sample. However, please note the large peak of cellular debris, partially cut-off, to the extreme left of the pulmonary MVEC and coronary artery histograms, as compared with the small or absent peaks for such cells exposed to normal and TTP plasmas shown in Fig 2.
