(A) Peak fasting triglyceride levels by time point of asparaginase therapy. (B) Peak calculated LDL levels by time point of asparaginase therapy. The boxplot distribution of fasting serum triglyceride (A) and calculated LDL (B) represent peak levels (in milligrams per deciliter) from serially obtained fasting lipid profiles on 38 newly diagnosed children with ALL before, during, and after asparaginase therapy. The plots also contain results from a one-time sample of 24 long-term survivors of childhood ALL. The boxplot describes the behavior of the measurements in the middle and ends of the distribution. The two ends of the box represent the first and third quartiles. The white line inside the box is the median. The tails of the distribution are illustrated by the whiskers. The extreme values beyond the whiskers, denoted by diamond-shaped points, represent the outliers. The horizontal dashed line represents the age-based normative value.